Each astrology sign has its own importance and affect the nature of native in its own way. Aries (mesha), Gemini (Mithuna), Leo (Simha) and Virgo (Kanya) are known as barren or sterile signs. These are not fruitful.
Barren signs on the cusps of the 5th and 11th house (11th house being 5th to partner) and the lords of these not in Fruitful sign, Moon not in a fruitful signs, the lagna not a fruitful sign the lord of lagna not occupying a fruitful sign and no fruitful sign, and no fruitful planet in 5th or 11th houses, are indications of no children.